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New Scientist recently published a quite long and confusing article about a mutation that has been identified as one of the most common causes of sudden death in children. The mutation in question is known as "hypertrophic cardiomyopathy" (HCM), which is characterized by an abnormal thickening of the walls of the heart. This thickening can interfere with the heart's ability to pump blood and can lead to serious complications, including sudden death. The article explains that the genetic mutation associated with HCM has only been identified within the past few years. It is passed down in families and is inherited in an autosomal dominant pattern, meaning that it only requires one copy of the gene from one parent to be expressed. The article goes on to discuss the challenges associated with diagnosing and treating HCM. It notes that there are no methods for detecting the gene before symptoms emerge, and that diagnosis relies on traditionally used methods like electrocardiographs and echocardiograms. Treatment is complicated by the fact that the exact cause of the mutation is incompletely understood, making symptom relief difficult. Overall, the article is an informative overview of hypertrophic cardiomyopathy, the mutation associated with it, and the challenges associated with diagnosing and treating it.

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